Loss of mpv17 affected early embryonic development via mitochondria dysfunction in zebrafish

MVP17 encodes a mitochondrial inner-membrane protein, and mutation of human MVP17 can cause mitochondria DNA depletion syndrome (MDDS). However, the underlying function of mpv17 is still elusive. Here, we developed a new mutant with mpv17 knockout by using the CRISPR/Cas9 system. The mpv17(−/−) zebr...

Descripción completa

Detalles Bibliográficos
Autores principales: Bian, Wan-Ping, Pu, Shi-Ya, Xie, Shao-Lin, Wang, Chao, Deng, Shun, Strauss, Phyllis R., Pei, De-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449779/
https://www.ncbi.nlm.nih.gov/pubmed/34537814
http://dx.doi.org/10.1038/s41420-021-00630-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449779/
https://www.ncbi.nlm.nih.gov/pubmed/34537814
http://dx.doi.org/10.1038/s41420-021-00630-w

Ejemplares similares