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B7-H5 blockade enhances CD8(+) T-cell-mediated antitumor immunity in colorectal cancer
Negative immune checkpoint blockade immunotherapy has shown potential for multiple malignancies including colorectal cancer (CRC). B7-H5, a novel negative immune checkpoint regulator, is highly expressed in tumor tissues and promotes tumor immune escape. However, the clinical significance of B7-H5 e...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449782/ https://www.ncbi.nlm.nih.gov/pubmed/34537815 http://dx.doi.org/10.1038/s41420-021-00628-4 |