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B7-H5 blockade enhances CD8(+) T-cell-mediated antitumor immunity in colorectal cancer

Negative immune checkpoint blockade immunotherapy has shown potential for multiple malignancies including colorectal cancer (CRC). B7-H5, a novel negative immune checkpoint regulator, is highly expressed in tumor tissues and promotes tumor immune escape. However, the clinical significance of B7-H5 e...

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Detalles Bibliográficos
Autores principales:	Wang, Jiayu, Wu, Hongya, Chen, Yanjun, Zhu, Jinghan, Sun, Linqing, Li, Juntao, Yao, Zhendong, Chen, Yuqi, Zhang, Xueguang, Xia, Suhua, Chen, Weichang, Shi, Tongguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449782/ https://www.ncbi.nlm.nih.gov/pubmed/34537815 http://dx.doi.org/10.1038/s41420-021-00628-4

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