A Semimechanistic Pharmacokinetic Model for Depot Medroxyprogesterone Acetate and Drug–Drug Interactions With Antiretroviral and Antituberculosis Treatment

Depot medroxyprogesterone acetate is an injectable hormonal contraceptive, widely used by women of childbearing potential living with HIV and/or tuberculosis. As medroxyprogesterone acetate is a cytochrome P450 (CYP3A4) substrate, drug–drug interactions (DDIs) with antiretroviral or antituberculosis...

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Detalles Bibliográficos
Autores principales: Francis, Jose, Mngqibisa, Rosie, McIlleron, Helen, Kendall, Michelle A, Wu, Xingye, Dooley, Kelly E., Firnhaber, Cynthia, Godfrey, Catherine, Cohn, Susan E., Denti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449800/
https://www.ncbi.nlm.nih.gov/pubmed/34151439
http://dx.doi.org/10.1002/cpt.2324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449800/
https://www.ncbi.nlm.nih.gov/pubmed/34151439
http://dx.doi.org/10.1002/cpt.2324

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