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Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs

BACKGROUND: Elastin degradation has been established as one of the driving factors of emphysema. Elastin-derived peptides (EDPs) are shown to act as a chemoattractant for monocytes. Effectively shielding elastin from elastolytic damage and regenerating lost elastin are two important steps in improvi...

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Detalles Bibliográficos
Autores principales:	Parasaram, Vaideesh, Wang, Xiaoying, Krisanarungson, Pantrika, Vyavahare, Narendra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449904/ https://www.ncbi.nlm.nih.gov/pubmed/34537081 http://dx.doi.org/10.1186/s12931-021-01838-1

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