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Association between circulating exhausted CD4(+) T cells with poor meningococcal C conjugate vaccine antibody response in HIV-infected children and adolescents

OBJECTIVES: To investigate the expression levels of surface markers of activation (CD38 and HLA-DR), inhibition (PD-1, TIGIT and CD57) and co-stimulation (CD28 and CD127) on CD4(+) T cells of children/adolescents with vertical HIV infection (HI patients) and HIV-uninfected (HU) controls vaccinated w...

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Detalles Bibliográficos
Autores principales: Silva, Giselle P., Pereira-Manfro, Wania F., Costa, Priscilla R., Costa, Dayane A., Ferreira, Bianca, Barreto, Daniela M., Frota, Ana Cristina C., Hofer, Cristina B., Figueredo, Carlos M., Coelho, Barbara, Kallas, Esper G., Milagres, Lucimar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449930/
https://www.ncbi.nlm.nih.gov/pubmed/34614112
http://dx.doi.org/10.6061/clinics/2021/e2902