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Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting

OBJECTIVES: Owing to the fact that obstructive sleep apnea (OSA) is an underreported disease, the strategy used for the diagnosis of OSA has been extensively dissected to devise a simplified process that can be accessed by the public health services. Polysomnography (PSG) type I, the gold standard f...

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Autores principales: da Rosa, João Carlos Fraga, Peres, Alessandra, Gasperin, Luciano, Martinez, Denis, Fontanella, Vania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Medicina / USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449931/
https://www.ncbi.nlm.nih.gov/pubmed/34614114
http://dx.doi.org/10.6061/clinics/2021/e3056
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author da Rosa, João Carlos Fraga
Peres, Alessandra
Gasperin, Luciano
Martinez, Denis
Fontanella, Vania
author_facet da Rosa, João Carlos Fraga
Peres, Alessandra
Gasperin, Luciano
Martinez, Denis
Fontanella, Vania
author_sort da Rosa, João Carlos Fraga
collection PubMed
description OBJECTIVES: Owing to the fact that obstructive sleep apnea (OSA) is an underreported disease, the strategy used for the diagnosis of OSA has been extensively dissected to devise a simplified process that can be accessed by the public health services. Polysomnography (PSG) type I, the gold standard for the diagnosis of OSA, is expensive and difficult to access by low-income populations. In this study, we aimed to verify the accuracy of the oxyhemoglobin desaturation index (ODI) in comparison to the apnea-hypopnea index (AHI) using a portable monitor. METHODS: We evaluated 94 type III PSG home test results of 65 elderly patients (69.21±6.94 years old), along with information, such as the body mass index (BMI) and sex, using data obtained from a clinical trial database. RESULTS: A significant linear positive correlation (r=0.93, p<0.05) was observed between ODI and AHI, without any interference from sex, BMI, and positional component. The sensitivity of ODI compared to that of AHI increased with an increase in the severity of OSA, while the specificity of ODI in comparison to that of AHI was high for all degrees of severity. The accuracy of ODI was 80.7% for distinguishing between patients with mild and moderate apnea and 84.4% for distinguishing between patients with moderate and severe apnea. CONCLUSION: The ODI values obtained in uncontrolled conditions exhibited high sensitivity for identifying severe apnea compared to the AHI values, and correctly identified the severity of OSA in more than 80% of the cases. Thus, oximetry is promising strategy for diagnosing OSA.
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spelling pubmed-84499312021-09-24 Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting da Rosa, João Carlos Fraga Peres, Alessandra Gasperin, Luciano Martinez, Denis Fontanella, Vania Clinics (Sao Paulo) Original Article OBJECTIVES: Owing to the fact that obstructive sleep apnea (OSA) is an underreported disease, the strategy used for the diagnosis of OSA has been extensively dissected to devise a simplified process that can be accessed by the public health services. Polysomnography (PSG) type I, the gold standard for the diagnosis of OSA, is expensive and difficult to access by low-income populations. In this study, we aimed to verify the accuracy of the oxyhemoglobin desaturation index (ODI) in comparison to the apnea-hypopnea index (AHI) using a portable monitor. METHODS: We evaluated 94 type III PSG home test results of 65 elderly patients (69.21±6.94 years old), along with information, such as the body mass index (BMI) and sex, using data obtained from a clinical trial database. RESULTS: A significant linear positive correlation (r=0.93, p<0.05) was observed between ODI and AHI, without any interference from sex, BMI, and positional component. The sensitivity of ODI compared to that of AHI increased with an increase in the severity of OSA, while the specificity of ODI in comparison to that of AHI was high for all degrees of severity. The accuracy of ODI was 80.7% for distinguishing between patients with mild and moderate apnea and 84.4% for distinguishing between patients with moderate and severe apnea. CONCLUSION: The ODI values obtained in uncontrolled conditions exhibited high sensitivity for identifying severe apnea compared to the AHI values, and correctly identified the severity of OSA in more than 80% of the cases. Thus, oximetry is promising strategy for diagnosing OSA. Faculdade de Medicina / USP 2021-09-20 2021 /pmc/articles/PMC8449931/ /pubmed/34614114 http://dx.doi.org/10.6061/clinics/2021/e3056 Text en Copyright © 2021 CLINICS https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ) which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
spellingShingle Original Article
da Rosa, João Carlos Fraga
Peres, Alessandra
Gasperin, Luciano
Martinez, Denis
Fontanella, Vania
Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
title Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
title_full Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
title_fullStr Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
title_full_unstemmed Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
title_short Diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
title_sort diagnostic accuracy of oximetry for obstructive sleep apnea: a study on older adults in a home setting
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449931/
https://www.ncbi.nlm.nih.gov/pubmed/34614114
http://dx.doi.org/10.6061/clinics/2021/e3056
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