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DNMT family induces down-regulation of NDRG1 via DNA methylation and clinicopathological significance in gastric cancer

BACKGROUND: Aberrant DNA methylation of tumor suppressor genes is a common event in the development and progression of gastric cancer (GC). Our previous study showed NDRG1, which could suppress cell invasion and migration, was frequently down-regulated by DNA methylation of its promoter in GC. PURPO...

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Detalles Bibliográficos
Autores principales: Chang, Xiaojing, Ma, Jinguo, Xue, Xiaoying, Wang, Guohui, Yan, Tianfang, Su, Linlin, Han, Xuetao, Zhou, Huandi, Hou, Liubing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450010/
https://www.ncbi.nlm.nih.gov/pubmed/34616614
http://dx.doi.org/10.7717/peerj.12146