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Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide

In Escherichia coli, elevated levels of free l-tryptophan (l-Trp) promote translational arrest of the TnaC peptide by inhibiting its termination. However, the mechanism by which translation-termination by the UGA-specific decoding release factor 2 (RF2) is inhibited at the UGA stop codon of stalled...

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Detalles Bibliográficos
Autores principales:	Su, Ting, Kudva, Renuka, Becker, Thomas, Buschauer, Robert, Komar, Tobias, Berninghausen, Otto, von Heijne, Gunnar, Cheng, Jingdong, Beckmann, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450073/ https://www.ncbi.nlm.nih.gov/pubmed/34403461 http://dx.doi.org/10.1093/nar/gkab665

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