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Development of a base editor for protein evolution via in situ mutation in vivo

Protein evolution has significantly enhanced the development of life science. However, it is difficult to achieve in vitro evolution of some special proteins because of difficulties with heterologous expression, purification, and function detection. To achieve protein evolution via in situ mutation...

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Detalles Bibliográficos
Autores principales: Hao, Wenliang, Cui, Wenjing, Cheng, Zhongyi, Han, Laichuang, Suo, Feiya, Liu, Zhongmei, Zhou, Li, Zhou, Zhemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450078/
https://www.ncbi.nlm.nih.gov/pubmed/34390349
http://dx.doi.org/10.1093/nar/gkab673

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