Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida

Macrolides have been effective clinical antibiotics for over 70 years. They inhibit protein biosynthesis in bacterial pathogens by narrowing the nascent protein exit tunnel in the ribosome. The macrolide class of natural products consist of a macrolactone ring linked to one or more sugar molecules....

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Detalles Bibliográficos
Autores principales: Breiner-Goldstein, Elinor, Eyal, Zohar, Matzov, Donna, Halfon, Yehuda, Cimicata, Giuseppe, Baum, Moti, Rokney, Assaf, Ezernitchi, Analia V, Lowell, Andrew N, Schmidt, Jennifer J, Rozenberg, Haim, Zimmerman, Ella, Bashan, Anat, Valinsky, Lea, Anzai, Yojiro, Sherman, David H, Yonath, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450085/
https://www.ncbi.nlm.nih.gov/pubmed/34417608
http://dx.doi.org/10.1093/nar/gkab684

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