Harnessing self-labeling enzymes for selective and concurrent A-to-I and C-to-U RNA base editing

The SNAP-ADAR tool enables precise and efficient A-to-I RNA editing in a guideRNA-dependent manner by applying the self-labeling SNAP-tag enzyme to generate RNA-guided editases in cell culture. Here, we extend this platform by combining the SNAP-tagged tool with further effectors steered by the orth...

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Detalles Bibliográficos
Autores principales: Stroppel, Anna S, Latifi, Ngadhnjim, Hanswillemenke, Alfred, Tasakis, Rafail Nikolaos, Papavasiliou, F Nina, Stafforst, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450088/
https://www.ncbi.nlm.nih.gov/pubmed/34197596
http://dx.doi.org/10.1093/nar/gkab541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450088/
https://www.ncbi.nlm.nih.gov/pubmed/34197596
http://dx.doi.org/10.1093/nar/gkab541

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