Deep and accurate detection of m(6)A RNA modifications using miCLIP2 and m6Aboost machine learning

N6-methyladenosine (m(6)A) is the most abundant internal RNA modification in eukaryotic mRNAs and influences many aspects of RNA processing. miCLIP (m(6)A individual-nucleotide resolution UV crosslinking and immunoprecipitation) is an antibody-based approach to map m(6)A sites with single-nucleotide...

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Detalles Bibliográficos
Autores principales: Körtel, Nadine, Rücklé, Cornelia, Zhou, You, Busch, Anke, Hoch-Kraft, Peter, Sutandy, F X Reymond, Haase, Jacob, Pradhan, Mihika, Musheev, Michael, Ostareck, Dirk, Ostareck-Lederer, Antje, Dieterich, Christoph, Hüttelmaier, Stefan, Niehrs, Christof, Rausch, Oliver, Dominissini, Dan, König, Julian, Zarnack, Kathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450095/
https://www.ncbi.nlm.nih.gov/pubmed/34157120
http://dx.doi.org/10.1093/nar/gkab485

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