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De-dimerization of PTB is catalyzed by PDI and is involved in the regulation of p53 translation

Polypyrimidine tract-binding protein (PTB) is an RNA binding protein existing both as dimer and monomer and shuttling between nucleus and cytoplasm. However, the regulation of PTB dimerization and the relationship between their functions and subcellular localization are unknown. Here we find that PT...

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Detalles Bibliográficos
Autores principales: Gong, Fu-Xing, Zhan, Guoqin, Han, Rong, Yang, Zhigang, Fu, Xin, Xiao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450096/
https://www.ncbi.nlm.nih.gov/pubmed/34403458
http://dx.doi.org/10.1093/nar/gkab708