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RbAp46/48(LIN-53) and HAT-1 are required for initial CENP-A(HCP-3) deposition and de novo holocentromere formation on artificial chromosomes in Caenorhabditis elegans embryos

Foreign DNA microinjected into the Caenorhabditis elegans syncytial gonad forms episomal extra-chromosomal arrays, or artificial chromosomes (ACs), in embryos. Short, linear DNA fragments injected concatemerize into high molecular weight (HMW) DNA arrays that are visible as punctate DAPI-stained foc...

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Detalles Bibliográficos
Autores principales:	Lin, Zhongyang, Yuen, Karen Wing Yee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450102/ https://www.ncbi.nlm.nih.gov/pubmed/33872374 http://dx.doi.org/10.1093/nar/gkab217

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