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Computational resources to define alleles and altered regulatory motifs at genomically edited candidate response elements

Unequivocal functional assessment of candidate genomic regulatory regions, such as transcriptional response elements, requires genetic alteration at their native chromosomal loci. Targeted DNA cleavage by Cas9 or other programmable nucleases enables analysis at virtually any genomic region, and dive...

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Detalles Bibliográficos
Autores principales:	Ehmsen, Kirk T, Knuesel, Matthew T, Martinez, Delsy, Asahina, Masako, Aridomi, Haruna, Yamamoto, Keith R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Data Resources and Analyses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450113/ https://www.ncbi.nlm.nih.gov/pubmed/34417596 http://dx.doi.org/10.1093/nar/gkab700

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