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Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study

PURPOSE: A high number of hospital admissions may indicate poor general health and less than optimal health care across sectors. To prevent hospital admissions, previous studies have focused on predicting readmissions relating to a defined index admission and specific condition, whereas generic mode...

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Autores principales: Skov Benthien, Kirstine, Kart Jacobsen, Rikke, Hjarnaa, Louise, Mehl Virenfeldt, Gert, Rasmussen, Knud, Toft, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450160/
https://www.ncbi.nlm.nih.gov/pubmed/34552360
http://dx.doi.org/10.2147/RMHP.S314588
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author Skov Benthien, Kirstine
Kart Jacobsen, Rikke
Hjarnaa, Louise
Mehl Virenfeldt, Gert
Rasmussen, Knud
Toft, Ulla
author_facet Skov Benthien, Kirstine
Kart Jacobsen, Rikke
Hjarnaa, Louise
Mehl Virenfeldt, Gert
Rasmussen, Knud
Toft, Ulla
author_sort Skov Benthien, Kirstine
collection PubMed
description PURPOSE: A high number of hospital admissions may indicate poor general health and less than optimal health care across sectors. To prevent hospital admissions, previous studies have focused on predicting readmissions relating to a defined index admission and specific condition, whereas generic models suited for community-dwelling persons are lacking. The aim of this study was to validate a generic model that predicted risk of emergency hospital admission within the following three months and to investigate regional variation. MATERIALS AND METHODS: This study is an observational register-based validation study of a prediction model. The prediction model was based on a population of frail elderly, persons with non-communicable diseases, and persons with three emergency hospital admissions using information about diagnoses and hospital contacts. The prediction model consisted of two stages. In the first stage, covariate associations to admissions are estimated from observed data in one year. In the second stage, admissions are predicted in the coming three months based on observed estimations from the first stage. The validity of the model was calculated by comparing predicted and observed admissions from August 1st to October 31st, 2016. RESULTS: The study included 112,026 persons. In nationwide data, area under the curve (AUC) was 0.7742 (95% CI 0.7698–0.7786), and the positive predictive value was 52% for the 99th percentile (the top 1%). AUC varied between regions from 0.6914 in Southern Denmark (95% CI 0.6779–0.7049) to 0.8224 (95% CI 0.8064–0.8384) in North Denmark. AUC was higher with nationwide data compared to regional. CONCLUSION: The model performed satisfactorily in predicting individual risk of emergency hospital admission.
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spelling pubmed-84501602021-09-21 Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study Skov Benthien, Kirstine Kart Jacobsen, Rikke Hjarnaa, Louise Mehl Virenfeldt, Gert Rasmussen, Knud Toft, Ulla Risk Manag Healthc Policy Original Research PURPOSE: A high number of hospital admissions may indicate poor general health and less than optimal health care across sectors. To prevent hospital admissions, previous studies have focused on predicting readmissions relating to a defined index admission and specific condition, whereas generic models suited for community-dwelling persons are lacking. The aim of this study was to validate a generic model that predicted risk of emergency hospital admission within the following three months and to investigate regional variation. MATERIALS AND METHODS: This study is an observational register-based validation study of a prediction model. The prediction model was based on a population of frail elderly, persons with non-communicable diseases, and persons with three emergency hospital admissions using information about diagnoses and hospital contacts. The prediction model consisted of two stages. In the first stage, covariate associations to admissions are estimated from observed data in one year. In the second stage, admissions are predicted in the coming three months based on observed estimations from the first stage. The validity of the model was calculated by comparing predicted and observed admissions from August 1st to October 31st, 2016. RESULTS: The study included 112,026 persons. In nationwide data, area under the curve (AUC) was 0.7742 (95% CI 0.7698–0.7786), and the positive predictive value was 52% for the 99th percentile (the top 1%). AUC varied between regions from 0.6914 in Southern Denmark (95% CI 0.6779–0.7049) to 0.8224 (95% CI 0.8064–0.8384) in North Denmark. AUC was higher with nationwide data compared to regional. CONCLUSION: The model performed satisfactorily in predicting individual risk of emergency hospital admission. Dove 2021-09-15 /pmc/articles/PMC8450160/ /pubmed/34552360 http://dx.doi.org/10.2147/RMHP.S314588 Text en © 2021 Skov Benthien et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Skov Benthien, Kirstine
Kart Jacobsen, Rikke
Hjarnaa, Louise
Mehl Virenfeldt, Gert
Rasmussen, Knud
Toft, Ulla
Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study
title Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study
title_full Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study
title_fullStr Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study
title_full_unstemmed Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study
title_short Predicting Individual Risk of Emergency Hospital Admissions – A Retrospective Validation Study
title_sort predicting individual risk of emergency hospital admissions – a retrospective validation study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450160/
https://www.ncbi.nlm.nih.gov/pubmed/34552360
http://dx.doi.org/10.2147/RMHP.S314588
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