Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity

Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study report...

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Detalles Bibliográficos
Autores principales: Correia, Ana M, Borges, Vítor, Isidro, Joana, Lima, Ana R, Fernandes, Alberto, Godinho, Maria Leonor, Duarte, Sílvia, Ferrão, José, Vieira, Luís, Gomes, João P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450161/
https://www.ncbi.nlm.nih.gov/pubmed/34547489
http://dx.doi.org/10.1016/j.ijid.2021.09.035
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author Correia, Ana M
Borges, Vítor
Isidro, Joana
Lima, Ana R
Fernandes, Alberto
Godinho, Maria Leonor
Duarte, Sílvia
Ferrão, José
Vieira, Luís
Gomes, João P
author_facet Correia, Ana M
Borges, Vítor
Isidro, Joana
Lima, Ana R
Fernandes, Alberto
Godinho, Maria Leonor
Duarte, Sílvia
Ferrão, José
Vieira, Luís
Gomes, João P
author_sort Correia, Ana M
collection PubMed
description Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.
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spelling pubmed-84501612021-09-20 Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity Correia, Ana M Borges, Vítor Isidro, Joana Lima, Ana R Fernandes, Alberto Godinho, Maria Leonor Duarte, Sílvia Ferrão, José Vieira, Luís Gomes, João P Int J Infect Dis Article Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases. The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021-11 2021-09-20 /pmc/articles/PMC8450161/ /pubmed/34547489 http://dx.doi.org/10.1016/j.ijid.2021.09.035 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Correia, Ana M
Borges, Vítor
Isidro, Joana
Lima, Ana R
Fernandes, Alberto
Godinho, Maria Leonor
Duarte, Sílvia
Ferrão, José
Vieira, Luís
Gomes, João P
Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_full Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_fullStr Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_full_unstemmed Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_short Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_sort potential recurrence of covid-19 in a healthcare professional: sars-cov-2 genome sequencing confirms contagiousness after re-positivity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450161/
https://www.ncbi.nlm.nih.gov/pubmed/34547489
http://dx.doi.org/10.1016/j.ijid.2021.09.035
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