The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19

Microcirculatory hemodynamic indexes (HI) were assessed in patients with moderate and severe COVID-19. In both groups, a significant increase in the absolute spectral indexes (HI1, HI2, and HI3) and the ratio of low-frequency to high-frequency component (HI1/HI3) was revealed. In the group of severe...

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Autores principales: Kuznik, B. I., Smolyakov, Yu. N., Shapovalov, Yu. K., Shapovalov, K. G., Lukyanov, S. A., Parts, D. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450309/
https://www.ncbi.nlm.nih.gov/pubmed/34542748
http://dx.doi.org/10.1007/s10517-021-05248-7
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author Kuznik, B. I.
Smolyakov, Yu. N.
Shapovalov, Yu. K.
Shapovalov, K. G.
Lukyanov, S. A.
Parts, D. S.
author_facet Kuznik, B. I.
Smolyakov, Yu. N.
Shapovalov, Yu. K.
Shapovalov, K. G.
Lukyanov, S. A.
Parts, D. S.
author_sort Kuznik, B. I.
collection PubMed
description Microcirculatory hemodynamic indexes (HI) were assessed in patients with moderate and severe COVID-19. In both groups, a significant increase in the absolute spectral indexes (HI1, HI2, and HI3) and the ratio of low-frequency to high-frequency component (HI1/HI3) was revealed. In the group of severe infection, only the “slow” index (low-frequency HI1) of microcirculatory hemodynamics was significantly lower. The oscillatory indices MAYER1-3 and RESP1-3 were reduced in patients of both groups. The aggravation of the disease course was accompanied by depression of the low-frequency index HI1. Regulatory shifts compensate for disturbances in microcirculatory processes in moderate COVID-19, but severe course was associated with their decompensation.
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spelling pubmed-84503092021-09-20 The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19 Kuznik, B. I. Smolyakov, Yu. N. Shapovalov, Yu. K. Shapovalov, K. G. Lukyanov, S. A. Parts, D. S. Bull Exp Biol Med Article Microcirculatory hemodynamic indexes (HI) were assessed in patients with moderate and severe COVID-19. In both groups, a significant increase in the absolute spectral indexes (HI1, HI2, and HI3) and the ratio of low-frequency to high-frequency component (HI1/HI3) was revealed. In the group of severe infection, only the “slow” index (low-frequency HI1) of microcirculatory hemodynamics was significantly lower. The oscillatory indices MAYER1-3 and RESP1-3 were reduced in patients of both groups. The aggravation of the disease course was accompanied by depression of the low-frequency index HI1. Regulatory shifts compensate for disturbances in microcirculatory processes in moderate COVID-19, but severe course was associated with their decompensation. Springer US 2021-09-20 2021 /pmc/articles/PMC8450309/ /pubmed/34542748 http://dx.doi.org/10.1007/s10517-021-05248-7 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Kuznik, B. I.
Smolyakov, Yu. N.
Shapovalov, Yu. K.
Shapovalov, K. G.
Lukyanov, S. A.
Parts, D. S.
The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19
title The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19
title_full The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19
title_fullStr The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19
title_full_unstemmed The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19
title_short The State of Microcirculatory Hemodynamics in Patients with Moderate and Severe COVID-19
title_sort state of microcirculatory hemodynamics in patients with moderate and severe covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450309/
https://www.ncbi.nlm.nih.gov/pubmed/34542748
http://dx.doi.org/10.1007/s10517-021-05248-7
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