Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management

Frailty is an age-related clinical syndrome that may increase the risk of falls, disability, hospitalization, and death in older adults. Delaying the progression of frailty helps improve the quality of life in older adults. Caloric restriction (CR) may extend lifespan and reduce the risk of age-rela...

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Detalles Bibliográficos
Autores principales: Liu, Pan, Li, Yun, Ma, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450361/
https://www.ncbi.nlm.nih.gov/pubmed/34552957
http://dx.doi.org/10.3389/fnut.2021.731356
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author Liu, Pan
Li, Yun
Ma, Lina
author_facet Liu, Pan
Li, Yun
Ma, Lina
author_sort Liu, Pan
collection PubMed
description Frailty is an age-related clinical syndrome that may increase the risk of falls, disability, hospitalization, and death in older adults. Delaying the progression of frailty helps improve the quality of life in older adults. Caloric restriction (CR) may extend lifespan and reduce the risk of age-related diseases. However, few studies have explored the relationship between CR and frailty. In this review, we focused on the impact of CR on frailty and aimed to identify potential associated mechanisms. Although CR may help prevent frailty, further studies are required to determine the underlying mechanisms and specific CR regimens suitable for use in humans.
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spelling pubmed-84503612021-09-21 Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management Liu, Pan Li, Yun Ma, Lina Front Nutr Nutrition Frailty is an age-related clinical syndrome that may increase the risk of falls, disability, hospitalization, and death in older adults. Delaying the progression of frailty helps improve the quality of life in older adults. Caloric restriction (CR) may extend lifespan and reduce the risk of age-related diseases. However, few studies have explored the relationship between CR and frailty. In this review, we focused on the impact of CR on frailty and aimed to identify potential associated mechanisms. Although CR may help prevent frailty, further studies are required to determine the underlying mechanisms and specific CR regimens suitable for use in humans. Frontiers Media S.A. 2021-09-06 /pmc/articles/PMC8450361/ /pubmed/34552957 http://dx.doi.org/10.3389/fnut.2021.731356 Text en Copyright © 2021 Liu, Li and Ma. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Liu, Pan
Li, Yun
Ma, Lina
Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management
title Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management
title_full Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management
title_fullStr Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management
title_full_unstemmed Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management
title_short Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management
title_sort caloric restriction may help delay the onset of frailty and support frailty management
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450361/
https://www.ncbi.nlm.nih.gov/pubmed/34552957
http://dx.doi.org/10.3389/fnut.2021.731356
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