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TRIM21/Ro52 - Roles in Innate Immunity and Autoimmune Disease

TRIM21 (Ro52/SSA1) is an E3 ubiquitin ligase with key roles in immune host defence, signal transduction, and possibly cell cycle regulation. It is also an autoantibody target in Sjögren’s syndrome, systemic lupus erythematosus, and other rheumatic autoimmune diseases. Here, we summarise the structur...

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Detalles Bibliográficos
Autores principales:	Jones, Esther L., Laidlaw, Stephen M., Dustin, Lynn B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450407/ https://www.ncbi.nlm.nih.gov/pubmed/34552597 http://dx.doi.org/10.3389/fimmu.2021.738473

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