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Driving CARs to BARs: The Winding Road to Specific Regulatory T Cells for Tolerance

Chimeric antigen receptor (CAR) transduced T cells have significantly improved cancer immunotherapy. Similarly, engineering regulatory T cells (Treg) with specific receptors to endow specificity and increase efficacy of Tregs holds great promise for therapy of a variety of adverse immune responses....

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Detalles Bibliográficos
Autor principal: Scott, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450509/
https://www.ncbi.nlm.nih.gov/pubmed/34552599
http://dx.doi.org/10.3389/fimmu.2021.742719