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Overexpression of Circular RNA circ_0013587 Reverses Erlotinib Resistance in Pancreatic Cancer Cells Through Regulating the miR-1227/E-Cadherin Pathway

BACKGROUND: Erlotinib, a small-molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, demonstrated therapeutic efficacy against pancreatic cancer. However, acquired resistance to erlotinib in pancreatic cancer is widely observed, and the exact mechanisms have not been fully expl...

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Detalles Bibliográficos
Autores principales:	Xu, Huiting, Chen, Runzhi, Shen, Qian, Yang, Dongmei, Peng, Hui, Tong, Jin, Fu, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450525/ https://www.ncbi.nlm.nih.gov/pubmed/34552882 http://dx.doi.org/10.3389/fonc.2021.754146

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