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RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells

High intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of irreversible blindness. Abnormal fibrotic activity in the human trabecular meshwork (HTM) cells is considered to be partly responsible for the increased resistance of aqueous humor outflow and IOP. This study aim...

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Detalles Bibliográficos
Autores principales: Liu, Zhicheng, Li, Shanshan, Qian, Xiuqing, Li, Lin, Zhang, Haixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450533/
https://www.ncbi.nlm.nih.gov/pubmed/34552960
http://dx.doi.org/10.3389/fmolb.2021.728932

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