Safety and preliminary efficacy of sequential multiple ascending doses of solnatide to treat pulmonary permeability edema in patients with moderate-to-severe ARDS—a randomized, placebo-controlled, double-blind trial

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a complex clinical diagnosis with various possible etiologies. One common feature, however, is pulmonary permeability edema, which leads to an increased alveolar diffusion pathway and, subsequently, impaired oxygenation and decarboxylation. A...

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Detalles Bibliográficos
Autores principales: Schmid, Benedikt, Kredel, Markus, Ullrich, Roman, Krenn, Katharina, Lucas, Rudolf, Markstaller, Klaus, Fischer, Bernhard, Kranke, Peter, Meybohm, Patrick, Zwißler, Bernhard, Frank, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450703/
https://www.ncbi.nlm.nih.gov/pubmed/34544463
http://dx.doi.org/10.1186/s13063-021-05588-9

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