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Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials

To date, treatment of atrophic acne scars remains a therapeutic challenge for dermatologists, yet there is no standard option on the most effective treatment. Microneedling (MN) is a minimally invasive technology that involves repetitive skin puncture using sterile microneedles to disrupt dermal col...

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Autores principales: Sitohang, Irma Bernadette S., Sirait, Sondang Aemilia Pandjaitan, Suryanegara, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450803/
https://www.ncbi.nlm.nih.gov/pubmed/33538106
http://dx.doi.org/10.1111/iwj.13559
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author Sitohang, Irma Bernadette S.
Sirait, Sondang Aemilia Pandjaitan
Suryanegara, Jose
author_facet Sitohang, Irma Bernadette S.
Sirait, Sondang Aemilia Pandjaitan
Suryanegara, Jose
author_sort Sitohang, Irma Bernadette S.
collection PubMed
description To date, treatment of atrophic acne scars remains a therapeutic challenge for dermatologists, yet there is no standard option on the most effective treatment. Microneedling (MN) is a minimally invasive technology that involves repetitive skin puncture using sterile microneedles to disrupt dermal collagen that connects the scar tissue. Recent studies have demonstrated the potency of MN, such as dermaroller and fractionated microneedle radiofrequency, in the treatment of atrophic scars. The objective of this review is to evaluate systematically the current literature on MN for atrophic acne scars. A systematic search of literature was performed from PubMed, Medline, Cochrane Central, and Google Scholar databases for articles published during the last 20 years. Only randomised controlled trials (RCTs) with full‐text version of the manuscript available were included in our study. Nine RCTs were included in this review. All treatment modalities demonstrated consistent results that MN was efficacious in treating atrophic acne scars as a monotherapy or in combination with other treatments. Moreover, no serious adverse effects were reported in all studies after MN treatment. MN is a well‐tolerated and effective therapeutic modality in treating atrophic acne scars. Further research is required to validate the efficacy of MN with a larger sample size and lengthy follow‐up.
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spelling pubmed-84508032021-09-27 Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials Sitohang, Irma Bernadette S. Sirait, Sondang Aemilia Pandjaitan Suryanegara, Jose Int Wound J Original Articles To date, treatment of atrophic acne scars remains a therapeutic challenge for dermatologists, yet there is no standard option on the most effective treatment. Microneedling (MN) is a minimally invasive technology that involves repetitive skin puncture using sterile microneedles to disrupt dermal collagen that connects the scar tissue. Recent studies have demonstrated the potency of MN, such as dermaroller and fractionated microneedle radiofrequency, in the treatment of atrophic scars. The objective of this review is to evaluate systematically the current literature on MN for atrophic acne scars. A systematic search of literature was performed from PubMed, Medline, Cochrane Central, and Google Scholar databases for articles published during the last 20 years. Only randomised controlled trials (RCTs) with full‐text version of the manuscript available were included in our study. Nine RCTs were included in this review. All treatment modalities demonstrated consistent results that MN was efficacious in treating atrophic acne scars as a monotherapy or in combination with other treatments. Moreover, no serious adverse effects were reported in all studies after MN treatment. MN is a well‐tolerated and effective therapeutic modality in treating atrophic acne scars. Further research is required to validate the efficacy of MN with a larger sample size and lengthy follow‐up. Blackwell Publishing Ltd 2021-02-03 /pmc/articles/PMC8450803/ /pubmed/33538106 http://dx.doi.org/10.1111/iwj.13559 Text en © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Sitohang, Irma Bernadette S.
Sirait, Sondang Aemilia Pandjaitan
Suryanegara, Jose
Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials
title Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials
title_full Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials
title_fullStr Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials
title_full_unstemmed Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials
title_short Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials
title_sort microneedling in the treatment of atrophic scars: a systematic review of randomised controlled trials
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450803/
https://www.ncbi.nlm.nih.gov/pubmed/33538106
http://dx.doi.org/10.1111/iwj.13559
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