The antidepressant Sertraline inhibits CatSper Ca(2+) channels in human sperm

STUDY QUESTION: Do selective serotonin reuptake inhibitor (SSRI) antidepressants affect the function of human sperm? SUMMARY ANSWER: The SSRI antidepressant Sertraline (e.g. Zoloft) inhibits the sperm-specific Ca(2+) channel CatSper and affects human sperm function in vitro. WHAT IS KNOWN ALREADY: I...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahban, Rita, Rehfeld, Anders, Schiffer, Christian, Brenker, Christoph, Egeberg Palme, Dorte Louise, Wang, Tao, Lorenz, Johannes, Almstrup, Kristian, Skakkebaek, Niels E, Strünker, Timo, Nef, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450872/
https://www.ncbi.nlm.nih.gov/pubmed/34486673
http://dx.doi.org/10.1093/humrep/deab190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450872/
https://www.ncbi.nlm.nih.gov/pubmed/34486673
http://dx.doi.org/10.1093/humrep/deab190

Ejemplares similares