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Base-free enantioselective S(N)2 alkylation of 2-oxindoles via bifunctional phase-transfer catalysis

N-Protected oxindole derivatives of unprecedented malleability bearing ester moieties at C-3 have been shown to participate in enantioselective phase-transfer-catalysed alkylations promoted by ad-hoc designed quaternary ammonium salts derived from quinine bearing hydrogen-bond donating substituents....

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Detalles Bibliográficos
Autores principales: Litvajova, Mili, Sorrentino, Emiliano, Twamley, Brendan, Connon, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450950/
https://www.ncbi.nlm.nih.gov/pubmed/34621391
http://dx.doi.org/10.3762/bjoc.17.146

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