Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1

Astrocytes express a plethora of G protein-coupled receptors (GPCRs) that are crucial for shaping synaptic activity. Upon GPCR activation, astrocytes can respond with transient variations in intracellular Ca(2+). In addition, Ca(2+)-dependent and/or Ca(2+)-independent release of gliotransmitters can...

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Detalles Bibliográficos
Autores principales: Van Den Herrewegen, Yana, Sanderson, Thomas M., Sahu, Surajit, De Bundel, Dimitri, Bortolotto, Zuner A., Smolders, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451082/
https://www.ncbi.nlm.nih.gov/pubmed/34544455
http://dx.doi.org/10.1186/s13041-021-00856-w

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