A new Mfn-2 related synthetic peptide promotes vascular smooth muscle cell apoptosis via regulating the mitochondrial apoptotic pathway by inhibiting Akt signaling

BACKGROUND: Restenosis after angioplasty is a major challenge for the treatment of coronary artery diseases. Facilitation of vascular smooth muscle cell (VSMC) apoptosis may be an attractive approach to decrease the incidence of restenosis. We synthesized a 16-amino acid mitofusin-2 (Mfn-2) gene rel...

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Detalles Bibliográficos
Autores principales: Zhang, Xinxin, Xu, Xiangyu, Lu, Li, Wan, Xiaoning, Qin, Yating, Ruan, Weibin, Lv, Chao, He, Lin, Guo, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451139/
https://www.ncbi.nlm.nih.gov/pubmed/34538249
http://dx.doi.org/10.1186/s12967-021-03064-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451139/
https://www.ncbi.nlm.nih.gov/pubmed/34538249
http://dx.doi.org/10.1186/s12967-021-03064-1

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