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DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker

BACKGROUND: Nucleotide-specific 5-hydroxymethylcytosine (5hmC) remains understudied in pediatric central nervous system (CNS) tumors. 5hmC is abundant in the brain, and alterations to 5hmC in adult CNS tumors have been reported. However, traditional approaches to measure DNA methylation do not disti...

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Detalles Bibliográficos
Autores principales:	Azizgolshani, Nasim, Petersen, Curtis L., Chen, Youdinghuan, Levy, Joshua J., Salas, Lucas A., Perreard, Laurent, Nguyen, Lananh N., Christensen, Brock C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451154/ https://www.ncbi.nlm.nih.gov/pubmed/34538273 http://dx.doi.org/10.1186/s13148-021-01156-9

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