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Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?

INTRODUCTION: To enhance the COVID-19 patients’ care and to optimize utilizing medical resources during the pandemic, relevant biomarkers are needed for prediction of the disease’s progression. The current study was aimed to determine the factors that affect the mortality of COVID-19 patients admitt...

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Autores principales: AKHAVIZADEGAN, HAMED, HOSAMIRUDSARI, HADISEH, ALIZADEH, MAHBOOBEH, ALIMOHAMADI, YOUSEF, KARBAKHSH DAVARI, MOJGAN, AKBARPOUR, SAMANEH, NAKHOSTIN-ANSARI, AMIN, FOROUGHI, ALIREZA, MANSURI, FARIBA, FARAJI, NEDA, NASIRI, ZOHREH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore Srl 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451338/
https://www.ncbi.nlm.nih.gov/pubmed/34604572
http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.2.1700
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author AKHAVIZADEGAN, HAMED
HOSAMIRUDSARI, HADISEH
ALIZADEH, MAHBOOBEH
ALIMOHAMADI, YOUSEF
KARBAKHSH DAVARI, MOJGAN
AKBARPOUR, SAMANEH
NAKHOSTIN-ANSARI, AMIN
FOROUGHI, ALIREZA
MANSURI, FARIBA
FARAJI, NEDA
NASIRI, ZOHREH
author_facet AKHAVIZADEGAN, HAMED
HOSAMIRUDSARI, HADISEH
ALIZADEH, MAHBOOBEH
ALIMOHAMADI, YOUSEF
KARBAKHSH DAVARI, MOJGAN
AKBARPOUR, SAMANEH
NAKHOSTIN-ANSARI, AMIN
FOROUGHI, ALIREZA
MANSURI, FARIBA
FARAJI, NEDA
NASIRI, ZOHREH
author_sort AKHAVIZADEGAN, HAMED
collection PubMed
description INTRODUCTION: To enhance the COVID-19 patients’ care and to optimize utilizing medical resources during the pandemic, relevant biomarkers are needed for prediction of the disease’s progression. The current study was aimed to determine the factors that affect the mortality of COVID-19 patients admitted in Baharloo hospital in Iran. METHODS: in the current retrospective study, 56 survived patients and 56 patients who were died (a total of 112 cases) because of COVID-19 infection were randomly selected from those who were admitted to Baharloo hospital. Each patient who was diagnosed with COVID-19 and had recovered from it matched with each non-survived patient in the term of age. Laboratory tests of all these patients at the time of admission were recorded and compared. All analyses performed using spss version 22 by considering α = 0.05 as a significant level. RESULTS: There was no statistical difference in the age and gender distribution between the two groups (p > 0.05). The prevalence of diabetes among survived patients was 37.5% and among non-survived patients was 26.8% and there was no statistical difference between two groups regarding this comorbidity (p = 0.22). Also, there was no statistical difference in the prevalence of hypertension and coronary heart diseases between two groups (p > 0.05). Lymphocyte percentage, blood oxygen level, and platelet (PLT) count was significantly higher in patients who had recovered (P < 0.05). CONCLUSIONS: LDH level, Lymphocyte percentage, PLT count, and blood Oxygen saturation have associations with severe forms of COVID-19 infection and can be used as predictors to assess the patients who are suspected of infection with COVID-19 at the time of admission.
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spelling pubmed-84513382021-10-01 Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19? AKHAVIZADEGAN, HAMED HOSAMIRUDSARI, HADISEH ALIZADEH, MAHBOOBEH ALIMOHAMADI, YOUSEF KARBAKHSH DAVARI, MOJGAN AKBARPOUR, SAMANEH NAKHOSTIN-ANSARI, AMIN FOROUGHI, ALIREZA MANSURI, FARIBA FARAJI, NEDA NASIRI, ZOHREH J Prev Med Hyg Review INTRODUCTION: To enhance the COVID-19 patients’ care and to optimize utilizing medical resources during the pandemic, relevant biomarkers are needed for prediction of the disease’s progression. The current study was aimed to determine the factors that affect the mortality of COVID-19 patients admitted in Baharloo hospital in Iran. METHODS: in the current retrospective study, 56 survived patients and 56 patients who were died (a total of 112 cases) because of COVID-19 infection were randomly selected from those who were admitted to Baharloo hospital. Each patient who was diagnosed with COVID-19 and had recovered from it matched with each non-survived patient in the term of age. Laboratory tests of all these patients at the time of admission were recorded and compared. All analyses performed using spss version 22 by considering α = 0.05 as a significant level. RESULTS: There was no statistical difference in the age and gender distribution between the two groups (p > 0.05). The prevalence of diabetes among survived patients was 37.5% and among non-survived patients was 26.8% and there was no statistical difference between two groups regarding this comorbidity (p = 0.22). Also, there was no statistical difference in the prevalence of hypertension and coronary heart diseases between two groups (p > 0.05). Lymphocyte percentage, blood oxygen level, and platelet (PLT) count was significantly higher in patients who had recovered (P < 0.05). CONCLUSIONS: LDH level, Lymphocyte percentage, PLT count, and blood Oxygen saturation have associations with severe forms of COVID-19 infection and can be used as predictors to assess the patients who are suspected of infection with COVID-19 at the time of admission. Pacini Editore Srl 2021-07-30 /pmc/articles/PMC8451338/ /pubmed/34604572 http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.2.1700 Text en ©2021 Pacini Editore SRL, Pisa, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en
spellingShingle Review
AKHAVIZADEGAN, HAMED
HOSAMIRUDSARI, HADISEH
ALIZADEH, MAHBOOBEH
ALIMOHAMADI, YOUSEF
KARBAKHSH DAVARI, MOJGAN
AKBARPOUR, SAMANEH
NAKHOSTIN-ANSARI, AMIN
FOROUGHI, ALIREZA
MANSURI, FARIBA
FARAJI, NEDA
NASIRI, ZOHREH
Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?
title Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?
title_full Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?
title_fullStr Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?
title_full_unstemmed Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?
title_short Can laboratory tests at the time of admission guide us to the prognosis of patients with COVID-19?
title_sort can laboratory tests at the time of admission guide us to the prognosis of patients with covid-19?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451338/
https://www.ncbi.nlm.nih.gov/pubmed/34604572
http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.2.1700
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