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Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital

BACKGROUND: Cancer is the second most common cause of deaths worldwide. Likewise, in India, it is a major health problem, and disease burden is escalating every year. Cancer chemotherapy produces unfavorable effects on the well‐being of an individual. Since the past few years, quality of life (QoL)...

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Autores principales: Ramasubbu, Saravana Kumar, Pasricha, Rajesh K., Nath, Uttam K., Rawat, Vikram Singh, Das, Biswadeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451381/
https://www.ncbi.nlm.nih.gov/pubmed/33295136
http://dx.doi.org/10.1002/cnr2.1312
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author Ramasubbu, Saravana Kumar
Pasricha, Rajesh K.
Nath, Uttam K.
Rawat, Vikram Singh
Das, Biswadeep
author_facet Ramasubbu, Saravana Kumar
Pasricha, Rajesh K.
Nath, Uttam K.
Rawat, Vikram Singh
Das, Biswadeep
author_sort Ramasubbu, Saravana Kumar
collection PubMed
description BACKGROUND: Cancer is the second most common cause of deaths worldwide. Likewise, in India, it is a major health problem, and disease burden is escalating every year. Cancer chemotherapy produces unfavorable effects on the well‐being of an individual. Since the past few years, quality of life (QoL) is considered as the main goal of cancer treatment in the survival of a patient. AIM: This current study aimed to assess the QoL and factors affecting it in adult cancer patients undergoing chemotherapy treatment. METHODS AND RESULTS: An analytical, cross‐sectional study was conducted to achieve the objectives, employing the consecutive sampling method. A total of 120 adult (>19 years) patients were recruited from daycare chemotherapy unit of a tertiary care hospital. The data were collected using patient record form and Functional Assessment of Cancer Therapy‐General (FACT‐G), a quality of life (QoL) questionnaire. The overall mean score of quality of life (QoL) was 61.933 ± 5.85502. The domains of functional well‐being and emotional well‐being were most negatively affected after cancer chemotherapy. Education (illiteracy) and occupation (unemployment) were negatively associated with overall quality of life (QoL) of cancer patients on chemotherapy. Adverse drug reactions due to cancer chemotherapy negatively affect the quality of life (QoL) of cancer patients. Education (illiteracy) affects social well‐being domain of cancer patients. Working in the government/private sector has a positive impact on functional well‐being domain of quality of life (QoL). CONCLUSION: The study findings suggest an overall low quality of life (QoL) among adult cancer patients undergoing chemotherapy at our setup. It has been identified as a stressful therapy, also affecting both psychological and physical well‐being. Poor infrastructure, illiteracy, poverty, and lack of proper treatment facilities at most centres often lead to poor survival outcomes and hence focus has always been on achieving quantity of life rather than quality of life (QoL). This is further complicated due to nonavailability of validated tools in local vernacular, apathy of the treating physicians in the context of QoL aspects and social and cultural factors that are unique to this society. Psycho‐oncology needs to become an integral entity of comprehensive cancer care.
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spelling pubmed-84513812021-09-27 Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital Ramasubbu, Saravana Kumar Pasricha, Rajesh K. Nath, Uttam K. Rawat, Vikram Singh Das, Biswadeep Cancer Rep (Hoboken) Original Articles BACKGROUND: Cancer is the second most common cause of deaths worldwide. Likewise, in India, it is a major health problem, and disease burden is escalating every year. Cancer chemotherapy produces unfavorable effects on the well‐being of an individual. Since the past few years, quality of life (QoL) is considered as the main goal of cancer treatment in the survival of a patient. AIM: This current study aimed to assess the QoL and factors affecting it in adult cancer patients undergoing chemotherapy treatment. METHODS AND RESULTS: An analytical, cross‐sectional study was conducted to achieve the objectives, employing the consecutive sampling method. A total of 120 adult (>19 years) patients were recruited from daycare chemotherapy unit of a tertiary care hospital. The data were collected using patient record form and Functional Assessment of Cancer Therapy‐General (FACT‐G), a quality of life (QoL) questionnaire. The overall mean score of quality of life (QoL) was 61.933 ± 5.85502. The domains of functional well‐being and emotional well‐being were most negatively affected after cancer chemotherapy. Education (illiteracy) and occupation (unemployment) were negatively associated with overall quality of life (QoL) of cancer patients on chemotherapy. Adverse drug reactions due to cancer chemotherapy negatively affect the quality of life (QoL) of cancer patients. Education (illiteracy) affects social well‐being domain of cancer patients. Working in the government/private sector has a positive impact on functional well‐being domain of quality of life (QoL). CONCLUSION: The study findings suggest an overall low quality of life (QoL) among adult cancer patients undergoing chemotherapy at our setup. It has been identified as a stressful therapy, also affecting both psychological and physical well‐being. Poor infrastructure, illiteracy, poverty, and lack of proper treatment facilities at most centres often lead to poor survival outcomes and hence focus has always been on achieving quantity of life rather than quality of life (QoL). This is further complicated due to nonavailability of validated tools in local vernacular, apathy of the treating physicians in the context of QoL aspects and social and cultural factors that are unique to this society. Psycho‐oncology needs to become an integral entity of comprehensive cancer care. John Wiley and Sons Inc. 2020-12-09 /pmc/articles/PMC8451381/ /pubmed/33295136 http://dx.doi.org/10.1002/cnr2.1312 Text en © 2020 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Ramasubbu, Saravana Kumar
Pasricha, Rajesh K.
Nath, Uttam K.
Rawat, Vikram Singh
Das, Biswadeep
Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
title Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
title_full Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
title_fullStr Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
title_full_unstemmed Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
title_short Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
title_sort quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451381/
https://www.ncbi.nlm.nih.gov/pubmed/33295136
http://dx.doi.org/10.1002/cnr2.1312
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