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Potential SARS-CoV-2 3CLpro inhibitors from chromene, flavonoid and hydroxamic acid compound based on FRET assay, docking and pharmacophore studies

This present study reports some natural products and one hydroxamic acid synthetic compound which were previously reported as matrix metalloproteinase-9 (MMP-9) inhibitors to be evaluated for their inhibition toward severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) 3-chymotrypsin-like pro...

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Detalles Bibliográficos
Autores principales: Hariono, Maywan, Hariyono, Pandu, Dwiastuti, Rini, Setyani, Wahyuning, Yusuf, Muhammad, Salin, Nurul, Wahab, Habibah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451405/
https://www.ncbi.nlm.nih.gov/pubmed/34567959
http://dx.doi.org/10.1016/j.rechem.2021.100195