Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

Tumor-initiating stem cells (TSCs) are critical for drug resistance and immune escape. However, the mutual regulations between TSC and tumor microenvironment (TME) remain unclear. Using DNA-label retaining, single-cell RNA sequencing (scRNA-seq), and other approaches, we investigated intestinal aden...

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Detalles Bibliográficos
Autores principales: He, Xi, Smith, Sarah E., Chen, Shiyuan, Li, Hua, Wu, Di, Meneses-Giles, Paloma I., Wang, Yongfu, Hembree, Mark, Yi, Kexi, Zhao, Xia, Guo, Fengli, Unruh, Jay R., Maddera, Lucinda E., Yu, Zulin, Scott, Allison, Perera, Anoja, Wang, Yan, Zhao, Chongbei, Bae, KyeongMin, Box, Andrew, Haug, Jeffrey S., Tao, Fang, Hu, Deqing, Hansen, Darrick M., Qian, Pengxu, Saha, Subhrajit, Dixon, Dan, Anant, Shrikant, Zhang, Da, Lin, Edward H., Sun, Weijing, Wiedemann, Leanne M., Li, Linheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451448/
https://www.ncbi.nlm.nih.gov/pubmed/34496236
http://dx.doi.org/10.1016/j.celrep.2021.109674

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