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Ursolic acid reverses liver fibrosis by inhibiting NOX4/NLRP3 inflammasome pathways and bacterial dysbiosis

Activation of the NOX4/NLRP3 inflammasome pathway has been associated with fibrosis in other organs. An imbalance in intestinal bacteria is an important driving factor of liver fibrosis through the liver-gut axis. This study aimed to explore whether the effect of ursolic acid (UA) on liver fibrosis...

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Detalles Bibliográficos
Autores principales: Nie, Yuan, Liu, Qi, Zhang, Wang, Wan, Yipeng, Huang, Chenkai, Zhu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451456/
https://www.ncbi.nlm.nih.gov/pubmed/34530693
http://dx.doi.org/10.1080/19490976.2021.1972746