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Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease

We analyzed the efficacy of penile low-intensity extracorporeal shockwave treatment for erectile dysfunction (ED) combined with cavernous artery disease (CAD). ED was evaluated by the International Index of Erectile Function, subdividing patients into mild and moderate/severe forms. CAD was assessed...

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Autores principales: Caretta, Nicola, De Rocco Ponce, Maurizio, Minicuci, Nadia, De Santis, Ilaria, Palego, Pierfrancesco, Garolla, Andrea, Foresta, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451489/
https://www.ncbi.nlm.nih.gov/pubmed/33753581
http://dx.doi.org/10.4103/aja.aja_15_21
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author Caretta, Nicola
De Rocco Ponce, Maurizio
Minicuci, Nadia
De Santis, Ilaria
Palego, Pierfrancesco
Garolla, Andrea
Foresta, Carlo
author_facet Caretta, Nicola
De Rocco Ponce, Maurizio
Minicuci, Nadia
De Santis, Ilaria
Palego, Pierfrancesco
Garolla, Andrea
Foresta, Carlo
author_sort Caretta, Nicola
collection PubMed
description We analyzed the efficacy of penile low-intensity extracorporeal shockwave treatment for erectile dysfunction (ED) combined with cavernous artery disease (CAD). ED was evaluated by the International Index of Erectile Function, subdividing patients into mild and moderate/severe forms. CAD was assessed using penile color Doppler ultrasonography. Patients (n = 111) with a positive outcome after treatment, based upon the minimal clinically important difference of the International Index of ED, were followed up for 3 months and 6 months. We found a significant mean increase in the index of erectile function, with an overall improvement in hemodynamic parameters of the cavernous artery. In particular, 93.9% of the patients with mild ED without CAD responded to treatment and 72.7% resumed normal erectile function. Only 31.2% of the patients with moderate/severe ED and CAD responded to treatment, and none resumed normal erectile function. All patients with mild ED and no CAD maintained the effects of therapy after 3 months, while no patients with moderate/severe ED and CAD maintained the benefits of treatment after 3 months. Thus, patients with mild ED and no CAD have better and longer lasting responses to such treatment, with a higher probability of resuming normal erectile function than patients with moderate/severe ED and CAD.
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spelling pubmed-84514892021-10-18 Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease Caretta, Nicola De Rocco Ponce, Maurizio Minicuci, Nadia De Santis, Ilaria Palego, Pierfrancesco Garolla, Andrea Foresta, Carlo Asian J Androl Original Article We analyzed the efficacy of penile low-intensity extracorporeal shockwave treatment for erectile dysfunction (ED) combined with cavernous artery disease (CAD). ED was evaluated by the International Index of Erectile Function, subdividing patients into mild and moderate/severe forms. CAD was assessed using penile color Doppler ultrasonography. Patients (n = 111) with a positive outcome after treatment, based upon the minimal clinically important difference of the International Index of ED, were followed up for 3 months and 6 months. We found a significant mean increase in the index of erectile function, with an overall improvement in hemodynamic parameters of the cavernous artery. In particular, 93.9% of the patients with mild ED without CAD responded to treatment and 72.7% resumed normal erectile function. Only 31.2% of the patients with moderate/severe ED and CAD responded to treatment, and none resumed normal erectile function. All patients with mild ED and no CAD maintained the effects of therapy after 3 months, while no patients with moderate/severe ED and CAD maintained the benefits of treatment after 3 months. Thus, patients with mild ED and no CAD have better and longer lasting responses to such treatment, with a higher probability of resuming normal erectile function than patients with moderate/severe ED and CAD. Wolters Kluwer - Medknow 2021-03-16 /pmc/articles/PMC8451489/ /pubmed/33753581 http://dx.doi.org/10.4103/aja.aja_15_21 Text en Copyright: ©The Author(s)(2021) https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Caretta, Nicola
De Rocco Ponce, Maurizio
Minicuci, Nadia
De Santis, Ilaria
Palego, Pierfrancesco
Garolla, Andrea
Foresta, Carlo
Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
title Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
title_full Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
title_fullStr Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
title_full_unstemmed Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
title_short Efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
title_sort efficacy of penile low-intensity shockwave treatment for erectile dysfunction: correlation with the severity of cavernous artery disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451489/
https://www.ncbi.nlm.nih.gov/pubmed/33753581
http://dx.doi.org/10.4103/aja.aja_15_21
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