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Polygalasaponin F protects hippocampal neurons against glutamate-induced cytotoxicity

Excess extracellular glutamate leads to excitotoxicity, which induces neuronal death through the overactivation of N-methyl-D-aspartate receptors (NMDARs). Excitotoxicity is thought to be closely related to various acute and chronic neurological disorders, such as stroke and Alzheimer’s disease. Pol...

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Detalles Bibliográficos
Autores principales: Sun, Chong, Cao, Xin-Cheng, Liu, Zhi-Yang, Ma, Chao-Lin, Li, Bao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451577/
https://www.ncbi.nlm.nih.gov/pubmed/34100454
http://dx.doi.org/10.4103/1673-5374.314321