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Discovery of facile amides-functionalized rhodanine-3-acetic acid derivatives as potential anticancer agents by disrupting microtubule dynamics

Microtubule dynamics are crucial for multiple cell functions, and cancer cells are particularly sensitive to microtubule-modulating agents. Here, we describe the design and synthesis of a series of (Z)-2-(5-benzylidene-4-oxo-2-thioxothiazolidin-3-yl)-N-phenylacetamide derivatives and evaluation of t...

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Detalles Bibliográficos
Autores principales:	Zhou, Xiang, Liu, Jiamin, Meng, Jiao, Fu, Yihong, Wu, Zhibin, Ouyang, Guiping, Wang, Zhenchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451688/ https://www.ncbi.nlm.nih.gov/pubmed/34525898 http://dx.doi.org/10.1080/14756366.2021.1975695

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