A reduced panel of eight genes (ATM, SF3B1, NOTCH1, BIRC3, XPO1, MYD88, TNFAIP3, and TP53) as an estimator of the tumor mutational burden in chronic lymphocytic leukemia

INTRODUCTION: Mutational complexity or tumor mutational burden (TMB) influences the course of chronic lymphocytic leukemia (CLL). However, this information is not routinely used because TMB is usually obtained from whole genome or exome, or from large gene panel high‐throughput sequencing. METHODS:...

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Detalles Bibliográficos
Autores principales: Chauzeix, Jasmine, Pastoret, Cédric, Donaty, Lucie, Gachard, Nathalie, Fest, Thierry, Feuillard, Jean, Rizzo, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451785/
https://www.ncbi.nlm.nih.gov/pubmed/33325634
http://dx.doi.org/10.1111/ijlh.13435

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