Cargando…

Keratinocyte‐derived IL‐1β induces PPARG downregulation and PPARD upregulation in human reconstructed epidermis following barrier impairment

Peroxisome proliferator‐activated receptors (PPARs) are a family of nuclear hormone receptors. In skin, PPARs modulate inflammation, lipid synthesis, keratinocyte differentiation and proliferation and thus are important for skin barrier homeostasis. Accordingly, PPAR expression is altered in various...

Descripción completa

Detalles Bibliográficos
Autores principales: Blunder, Stefan, Krimbacher, Thomas, Moosbrugger‐Martinz, Verena, Gruber, Robert, Schmuth, Matthias, Dubrac, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451818/
https://www.ncbi.nlm.nih.gov/pubmed/33683743
http://dx.doi.org/10.1111/exd.14323