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Keratinocyte‐derived IL‐1β induces PPARG downregulation and PPARD upregulation in human reconstructed epidermis following barrier impairment
Peroxisome proliferator‐activated receptors (PPARs) are a family of nuclear hormone receptors. In skin, PPARs modulate inflammation, lipid synthesis, keratinocyte differentiation and proliferation and thus are important for skin barrier homeostasis. Accordingly, PPAR expression is altered in various...
Autores principales: | Blunder, Stefan, Krimbacher, Thomas, Moosbrugger‐Martinz, Verena, Gruber, Robert, Schmuth, Matthias, Dubrac, Sandrine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451818/ https://www.ncbi.nlm.nih.gov/pubmed/33683743 http://dx.doi.org/10.1111/exd.14323 |
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