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Ivabradine improves survival and attenuates cardiac remodeling in isoproterenol‐induced myocardial injury

This study investigated whether ivabradine, a selective I(f) current inhibitor reducing heart rate (HR), is able to improve survival and prevent left ventricular (LV) remodeling in isoproterenol‐induced heart damage. Wistar rats were treated for 6 weeks: controls (n = 10), ivabradine (10 mg/kg/day o...

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Detalles Bibliográficos
Autores principales: Simko, Fedor, Baka, Tomas, Repova, Kristina, Aziriova, Silvia, Krajcirovicova, Kristina, Paulis, Ludovit, Adamcova, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451821/
https://www.ncbi.nlm.nih.gov/pubmed/33098700
http://dx.doi.org/10.1111/fcp.12620