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Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample
AIM: Suicidal thoughts and behaviours are prevalent in individuals with schizophrenia. However, research examining the prevalence and predictors of suicidality and self‐harm in participants at clinical high‐risk for psychosis (CHR‐P) is limited and mostly focuses on help‐seeking participants recruit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Publishing Asia Pty Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451831/ https://www.ncbi.nlm.nih.gov/pubmed/33372364 http://dx.doi.org/10.1111/eip.13075 |
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author | Haining, Kate Karagiorgou, Olga Gajwani, Ruchika Gross, Joachim Gumley, Andrew I. Lawrie, Stephen M. Schwannauer, Matthias Schultze‐Lutter, Frauke Uhlhaas, Peter J. |
author_facet | Haining, Kate Karagiorgou, Olga Gajwani, Ruchika Gross, Joachim Gumley, Andrew I. Lawrie, Stephen M. Schwannauer, Matthias Schultze‐Lutter, Frauke Uhlhaas, Peter J. |
author_sort | Haining, Kate |
collection | PubMed |
description | AIM: Suicidal thoughts and behaviours are prevalent in individuals with schizophrenia. However, research examining the prevalence and predictors of suicidality and self‐harm in participants at clinical high‐risk for psychosis (CHR‐P) is limited and mostly focuses on help‐seeking participants recruited through clinical pathways. The current study sought to assess the prevalence of suicidality and self‐harm and identify predictors of current suicidal ideation in community‐recruited CHR‐P participants. METHODS: Data were available for 130 CHR‐P participants, 15 participants with first‐episode psychosis (FEP), 47 participants not fulfilling CHR‐P criteria (CHR‐Ns) and 53 healthy controls. Current and lifetime suicidality and self‐harm were assessed using the Mini‐International Neuropsychiatric Interview and the Comprehensive Assessment of At‐Risk Mental States (CAARMS). Multivariable logistic regression analysis was used to determine predictors of current suicidal ideation in the CHR‐P group. RESULTS: A considerable proportion of CHR‐P participants disclosed current suicidal ideation (34.6%). Overall, FEP individuals were at greatest risk, with considerably high prevalence rates for current suicidal ideation (73.3%), lifetime self‐harm behaviour (60.0%) and lifetime suicide attempt (60.0%). In the CHR‐P sample, current suicidal ideation was predicted by lifetime suicide attempts, lower CAARMS severity, impaired social functioning and greater comorbidity. CONCLUSIONS: Our findings suggest that suicidality and self‐harm are highly prevalent in community‐recruited CHR‐P and FEP individuals. Accordingly, these results highlight the importance of further research into the determinants of suicidality and self‐harm during at‐risk and early stages of psychosis, and the implementation of intervention strategies to reduce adverse outcomes in these populations. |
format | Online Article Text |
id | pubmed-8451831 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wiley Publishing Asia Pty Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-84518312021-09-27 Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample Haining, Kate Karagiorgou, Olga Gajwani, Ruchika Gross, Joachim Gumley, Andrew I. Lawrie, Stephen M. Schwannauer, Matthias Schultze‐Lutter, Frauke Uhlhaas, Peter J. Early Interv Psychiatry Original Articles AIM: Suicidal thoughts and behaviours are prevalent in individuals with schizophrenia. However, research examining the prevalence and predictors of suicidality and self‐harm in participants at clinical high‐risk for psychosis (CHR‐P) is limited and mostly focuses on help‐seeking participants recruited through clinical pathways. The current study sought to assess the prevalence of suicidality and self‐harm and identify predictors of current suicidal ideation in community‐recruited CHR‐P participants. METHODS: Data were available for 130 CHR‐P participants, 15 participants with first‐episode psychosis (FEP), 47 participants not fulfilling CHR‐P criteria (CHR‐Ns) and 53 healthy controls. Current and lifetime suicidality and self‐harm were assessed using the Mini‐International Neuropsychiatric Interview and the Comprehensive Assessment of At‐Risk Mental States (CAARMS). Multivariable logistic regression analysis was used to determine predictors of current suicidal ideation in the CHR‐P group. RESULTS: A considerable proportion of CHR‐P participants disclosed current suicidal ideation (34.6%). Overall, FEP individuals were at greatest risk, with considerably high prevalence rates for current suicidal ideation (73.3%), lifetime self‐harm behaviour (60.0%) and lifetime suicide attempt (60.0%). In the CHR‐P sample, current suicidal ideation was predicted by lifetime suicide attempts, lower CAARMS severity, impaired social functioning and greater comorbidity. CONCLUSIONS: Our findings suggest that suicidality and self‐harm are highly prevalent in community‐recruited CHR‐P and FEP individuals. Accordingly, these results highlight the importance of further research into the determinants of suicidality and self‐harm during at‐risk and early stages of psychosis, and the implementation of intervention strategies to reduce adverse outcomes in these populations. Wiley Publishing Asia Pty Ltd 2020-12-28 2021-10 /pmc/articles/PMC8451831/ /pubmed/33372364 http://dx.doi.org/10.1111/eip.13075 Text en © 2020 The Authors. Early Intervention in Psychiatry Published by John Wiley & Sons Australia, Ltd https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Haining, Kate Karagiorgou, Olga Gajwani, Ruchika Gross, Joachim Gumley, Andrew I. Lawrie, Stephen M. Schwannauer, Matthias Schultze‐Lutter, Frauke Uhlhaas, Peter J. Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample |
title | Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample |
title_full | Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample |
title_fullStr | Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample |
title_full_unstemmed | Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample |
title_short | Prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: Results from a community‐recruited sample |
title_sort | prevalence and predictors of suicidality and non‐suicidal self‐harm among individuals at clinical high‐risk for psychosis: results from a community‐recruited sample |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451831/ https://www.ncbi.nlm.nih.gov/pubmed/33372364 http://dx.doi.org/10.1111/eip.13075 |
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