Cargando…
Prostacyclin analog beraprost sodium efficacy in primary glomerular disease or nephrosclerosis: Analysis of the Japanese subgroup in CASSIOPEIR study
We conducted a multicenter, randomized, double‐blind, placebo‐controlled, phase IIb/III study (CASSIOPEIR) using a renal composite endpoint (i.e., doubling of SCr or end‐stage renal disease) in seven Asian countries/region. CASSIOPEIR compared TRK‐100STP (120 μg and 240 μg) with placebo in patients...
Autores principales: | Kurumatani, Hajimu, Okada, Kiyonobu, Origasa, Hideki, Fujita, Toshiro, Isono, Masanao, Nakamoto, Hidetomo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451904/ https://www.ncbi.nlm.nih.gov/pubmed/33340238 http://dx.doi.org/10.1111/1744-9987.13616 |
Ejemplares similares
-
A multinational phase IIb/III trial of beraprost sodium, an orally active prostacyclin analogue, in patients with primary glomerular disease or nephrosclerosis (CASSIOPEIR trial), rationale and study design
por: Nakamoto, Hidetomo, et al.
Publicado: (2014) -
Orally active prostacyclin analogue beraprost sodium in patients with chronic kidney disease: a randomized, double-blind, placebo-controlled, phase II dose finding trial
por: Koyama, Akio, et al.
Publicado: (2015) -
The Prostacyclin Analog Beraprost Sodium Ameliorates Characteristics of Metabolic Syndrome in Obese Zucker (Fatty) Rats
por: Sato, Nahoko, et al.
Publicado: (2010) -
Hypertension, glomerular hypertrophy and nephrosclerosis: the effect of race
por: Hughson, Michael D., et al.
Publicado: (2014) -
Prostacyclin Analogue Beraprost Inhibits Cardiac Fibroblast Proliferation Depending on Prostacyclin Receptor Activation through a TGF β-Smad Signal Pathway
por: Chen, Yun, et al.
Publicado: (2014)