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Automated monitoring of respiratory rate as a novel humane endpoint: A refinement in mouse metastatic lung cancer models
In oncology research, while xenograft tumor models are easily visualized and humane endpoints can be clearly defined, metastatic tumor models are often based on more subjective clinical observations as endpoints. This study aimed at identifying objective non-invasive criteria for predicting imminent...
Autores principales: | Winn, Caroline B., Hwang, Seo-Kyoung, Morin, Jeffrey, Bluette, Crystal T., Manickam, Balasubramanian, Jiang, Ziyue K., Giddabasappa, Anand, Liu, Chang-Ning, Matthews, Kristin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452061/ https://www.ncbi.nlm.nih.gov/pubmed/34543354 http://dx.doi.org/10.1371/journal.pone.0257694 |
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