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Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2

Given the importance of variant SARS-CoV-2 viruses with altered receptor-binding or antigenic phenotypes, we sought to quantify the degree to which adaptive evolution is driving accumulation of mutations in the SARS-CoV-2 genome. Here we assessed adaptive evolution across genes in the SARS-CoV-2 gen...

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Detalles Bibliográficos
Autores principales: Kistler, Kathryn E., Huddleston, John, Bedford, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452090/
https://www.ncbi.nlm.nih.gov/pubmed/34545361
http://dx.doi.org/10.1101/2021.09.11.459844