Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

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Novel strategies are needed to identify drug targets and treatments for the COVID-19 pandemic. The altered gene expression of virus-infected host cells provides an opportunity to specifically inhibit viral propagation via targeting the synthetic lethal (SL) partners of such altered host genes. Pursu...

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Detalles Bibliográficos
Autores principales: Pal, Lipika R., Cheng, Kuoyuan, Nair, Nishanth Ulhas, Martin-Sancho, Laura, Sinha, Sanju, Pu, Yuan, Riva, Laura, Yin, Xin, Schischlik, Fiorella, Lee, Joo Sang, Chanda, Sumit K., Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452092/
https://www.ncbi.nlm.nih.gov/pubmed/34545363
http://dx.doi.org/10.1101/2021.09.14.460408
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