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Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients

BACKGROUND: Dental biofilm plays a crucial role in periodontal disease development. Mouth rinse is used to enhance oral hygiene after scaling and root planning (SRP). The aim of the study was to evaluate the clinical and microbiological effectiveness of a piper extract mouthwash against Chlorhexidin...

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Autores principales: Sundaram, Gopalakrishnan, Theagarajan, Ramakrishnan, Murthy, Gomathi Dhakshina, Kanimozhi, Gopalakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452170/
https://www.ncbi.nlm.nih.gov/pubmed/34667385
http://dx.doi.org/10.4103/jisp.jisp_509_20
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author Sundaram, Gopalakrishnan
Theagarajan, Ramakrishnan
Murthy, Gomathi Dhakshina
Kanimozhi, Gopalakrishnan
author_facet Sundaram, Gopalakrishnan
Theagarajan, Ramakrishnan
Murthy, Gomathi Dhakshina
Kanimozhi, Gopalakrishnan
author_sort Sundaram, Gopalakrishnan
collection PubMed
description BACKGROUND: Dental biofilm plays a crucial role in periodontal disease development. Mouth rinse is used to enhance oral hygiene after scaling and root planning (SRP). The aim of the study was to evaluate the clinical and microbiological effectiveness of a piper extract mouthwash against Chlorhexidine (CHX) in periodontitis patients. MATERIALS AND METHODS: Sixty patients with Stage II periodontitis participated in this study and were randomly divided into two groups (Group I – Stage II Grade A periodontitis patients were provided with prepared piper extract mouthwash and Group II – Stage II Grade A periodontitis patients were provided with 0.2% CHX). Plaque index, gingival index, sulcus bleeding index, probing pocket depth, and clinical attachment level were recorded at baseline and 30 days after SRP. Subgingival plaque samples were taken for microbial examination (colony-forming unit), quantification of Porphyromonas gingivalis using the real-time polymerase chain reaction at baseline, and 30 days after SRP. RESULTS: Intragroup comparison for the clinical parameters showed statistically significant reduction in both the groups (P < 0.0001). Intergroup comparison for clinical parameters, there was no statistical significance seen after 30 days. Intragroup comparison for microbial analysis showed significant reduction in both the groups after 30 days (P < 0.0001). On intergroup comparison for microbial analysis, both the groups showed reduction after 30 days without significance. CONCLUSION: Piper extract mouthwash (Group I) showed similar antimicrobial activity against P. gingivalis when compared to 0.2% CHX mouthwash (Group II) that could be used as a substitute to CHX.
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spelling pubmed-84521702021-10-18 Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients Sundaram, Gopalakrishnan Theagarajan, Ramakrishnan Murthy, Gomathi Dhakshina Kanimozhi, Gopalakrishnan J Indian Soc Periodontol Original Article BACKGROUND: Dental biofilm plays a crucial role in periodontal disease development. Mouth rinse is used to enhance oral hygiene after scaling and root planning (SRP). The aim of the study was to evaluate the clinical and microbiological effectiveness of a piper extract mouthwash against Chlorhexidine (CHX) in periodontitis patients. MATERIALS AND METHODS: Sixty patients with Stage II periodontitis participated in this study and were randomly divided into two groups (Group I – Stage II Grade A periodontitis patients were provided with prepared piper extract mouthwash and Group II – Stage II Grade A periodontitis patients were provided with 0.2% CHX). Plaque index, gingival index, sulcus bleeding index, probing pocket depth, and clinical attachment level were recorded at baseline and 30 days after SRP. Subgingival plaque samples were taken for microbial examination (colony-forming unit), quantification of Porphyromonas gingivalis using the real-time polymerase chain reaction at baseline, and 30 days after SRP. RESULTS: Intragroup comparison for the clinical parameters showed statistically significant reduction in both the groups (P < 0.0001). Intergroup comparison for clinical parameters, there was no statistical significance seen after 30 days. Intragroup comparison for microbial analysis showed significant reduction in both the groups after 30 days (P < 0.0001). On intergroup comparison for microbial analysis, both the groups showed reduction after 30 days without significance. CONCLUSION: Piper extract mouthwash (Group I) showed similar antimicrobial activity against P. gingivalis when compared to 0.2% CHX mouthwash (Group II) that could be used as a substitute to CHX. Wolters Kluwer - Medknow 2021 2021-08-30 /pmc/articles/PMC8452170/ /pubmed/34667385 http://dx.doi.org/10.4103/jisp.jisp_509_20 Text en Copyright: © 2021 Indian Society of Periodontology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sundaram, Gopalakrishnan
Theagarajan, Ramakrishnan
Murthy, Gomathi Dhakshina
Kanimozhi, Gopalakrishnan
Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients
title Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients
title_full Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients
title_fullStr Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients
title_full_unstemmed Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients
title_short Effect of piper extract mouthwash as postprocedural rinse on levels of Porphyromonas gingivalis in periodontitis patients
title_sort effect of piper extract mouthwash as postprocedural rinse on levels of porphyromonas gingivalis in periodontitis patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452170/
https://www.ncbi.nlm.nih.gov/pubmed/34667385
http://dx.doi.org/10.4103/jisp.jisp_509_20
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