Precision dosing of intravenous busulfan in pediatric hematopoietic stem cell transplantation: Results from a multicenter population pharmacokinetic study

Busulfan (Bu) is a common component of conditioning regimens before hematopoietic stem cell transplantation (HSCT) and is known for high interpatient pharmacokinetic (PK) variability. This study aimed to develop and externally validate a multicentric, population PK (PopPK) model for intravenous Bu i...

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Detalles Bibliográficos
Autores principales: Ben Hassine, Khalil, Nava, Tiago, Théoret, Yves, Nath, Christa E., Daali, Youssef, Kassir, Nastya, Lewis, Victor, Bredius, Robbert G. M., Shaw, Peter J., Bittencourt, Henrique, Krajinovic, Maja, Uppugunduri, Chakradhara Rao Satyanarayana, Ansari, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452291/
https://www.ncbi.nlm.nih.gov/pubmed/34453497
http://dx.doi.org/10.1002/psp4.12683

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